Anaplastic large cell lymphoma, ALK positive
50 year old with an abdominal mass. Core biopsy shows sheets of atypical large cells with abundant cytoplasm associated with patchy necrosis. These …
14 Sep
CMV colitis
CMV colitis
60 year old man post chemotherapy for CLL. Now with diarrhea and abdominal pain.
20 Aug
Rhabdomyosarcoma
Rhabdomyosarcoma
H&E Bone marrow biopsy from an 85-year-old female. The tumor cells lack expression of MPO, TdT, Hemoglobin A, Glycophorin A, lysozyme, CD30, and pax-5 arguing against hematopoietic origin. …
18 Aug
Pulmonary crystal-rich histiocytoma
Pulmonary crystal-rich histiocytoma
The photomicrographs are from a 67 year old woman with a right lung mass composed of histiocytes (CD163 positive) with numerous crystalline deposits of immunoglobulin. …
17 Aug
Extramedullary hematopoiesis
Extramedullary hematopoiesis
61 year old male with hepatitis. Scattered megakaryocytes with a few clusters of erythroid precursors present. The megakaryocytes are positive for CD42b.
11 Aug
Angiomyolipoma
Angiomyolipoma
78 year old woman with a right renal mass. The tumor is composed of spindle cells, fat and hyalinized blood vessels. Keratin studies …
10 Aug
Pleomorphic sarcoma
Pleomorphic sarcoma
55 year old woman with a left posterior thigh mass. Histology shows a pleomorphic spindle cell tumor with numerous atypical mitotic figures (6/hpf) highlighted …