Anaplastic large cell lymphoma, ALK positive

Anaplastic large cell lymphoma, ALK positive

50 year old with an abdominal mass. Core biopsy shows sheets of atypical large cells with abundant cytoplasm associated with patchy necrosis. These …

 

CMV colitis

CMV colitis

60 year old man post chemotherapy for CLL. Now with diarrhea and abdominal pain.

 

Rhabdomyosarcoma

Rhabdomyosarcoma

H&E Bone marrow biopsy from an 85-year-old female. The tumor cells lack expression of MPO, TdT, Hemoglobin A, Glycophorin A, lysozyme, CD30, and pax-5 arguing against hematopoietic origin. …

 

Pulmonary crystal-rich histiocytoma

Pulmonary crystal-rich histiocytoma

The photomicrographs are from a 67 year old woman with a right lung mass composed of histiocytes (CD163 positive) with numerous crystalline deposits of immunoglobulin. …

 

Extramedullary hematopoiesis

Extramedullary hematopoiesis

61 year old male with hepatitis. Scattered megakaryocytes with a few clusters of erythroid precursors present. The megakaryocytes are positive for CD42b.

 

Angiomyolipoma

Angiomyolipoma

78 year old woman with a right renal mass. The tumor is composed of spindle cells, fat and hyalinized blood vessels. Keratin studies …

 

Pleomorphic sarcoma

Pleomorphic sarcoma

55 year old woman with a left posterior thigh mass. Histology shows a pleomorphic spindle cell tumor with numerous atypical mitotic figures (6/hpf) highlighted …